Featured ArticleDisease Intelligence
Why Disease Intelligence Comes Before Target Selection
A field note on disease states, patient-relevant biology, and why target discovery needs a richer operating model.
May 2026 / 7 min read
Insights
Insights on AI, disease biology, and the future of therapeutic discovery.
Research notes, essays, technical perspectives, and field analysis from the frontier of disease intelligence.
Disease IntelligenceTherapeutic HypothesesIn Silico MedicineTranslational MedicineAI Drug DiscoveryAlzheimer’s ResearchPlatform NotesFounder EssaysEvidence GraphsPerturbation ModelingValidation Design
Research NoteTherapeutic Hypotheses
What Makes a Therapeutic Hypothesis Testable?
A compact template for linking subtype, perturbation, expected outcome, and confidence.
May 2026 / 4 min read
Field MapAI Drug Discovery
From Perturbation Logic to Modality Choice
How intervention type changes when the biological action is activation, inhibition, degradation, or modulation.
May 2026 / 6 min read
Founder EssayFounder Essays
The Bottleneck Is Understanding
Faster generation does not solve uncertainty. Better maps do.
May 2026 / 5 min read
Standard ArticlePlatform Notes
Evidence Graphs for Defensible AI Biology
Why recommendations need provenance, contradiction handling, confidence scoring, and explicit gaps.
May 2026 / 8 min read
Research NoteTranslational Medicine
Validation Packages as Decision Products
The path from hypothesis to biomarker strategy, assay design, model selection, and translational readout.
May 2026 / 6 min read
Standard ArticleAlzheimer’s Research
Alzheimer’s as a Systems Problem
A short perspective on disease heterogeneity, mechanism-level subtyping, and intervention timing.
May 2026 / 9 min read
Field MapDisease Intelligence
Mechanism Maps for Patient Subtypes
How subtype-aware maps can make competing intervention paths easier to compare.
May 2026 / 6 min read
Research NoteIn Silico Medicine
Perturbation Confidence Is Not a Single Number
A short note on mechanism confidence, evidence maturity, translation risk, and uncertainty windows.
May 2026 / 5 min read
Founder EssayFounder Essays
From Prediction to Proof
Why the best AI biology systems should be judged by how they improve the next experiment.
May 2026 / 7 min read
Standard ArticleTranslational Medicine
Designing Validation Around Human Relevance
Biomarkers, endpoints, model systems, and readouts that make hypotheses decision-ready.
May 2026 / 8 min read
Research NoteTherapeutic Hypotheses
When Modality Follows Mechanism
Why the same target can imply different therapeutic forms depending on the required biological action.
May 2026 / 4 min read
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